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According to the American Medical Express, scientists at the University of Milan Bicca found that the nerve health of the human body depends on the signals from the leg muscles to the brain, and the exercise of the legs can play a role in the maintenance of nerves.

The researchers experimented with mice and restricted them to use the hind legs within 28 days. In the meantime, the mice normally ate and combed the fur and did not show a stress response. At the end of the experiment, the researchers examined a region of their brain called the subventricular zone. In many mammals, this region has the role of maintaining nerve cell health and is where stem cells produce new neurons. The results showed that the number of neural stem cells in mice restricted by leg activity was reduced by 70% compared to control mice that were not restrained. In addition, mouse neurons and oligodendrocytes (special cells supporting and isolating nerve cells) are not fully mature when the amount of exercise is drastically reduced.

The researchers point out that the use of leg muscle strength in weight-bearing exercise causes the brain to receive specific signals that are critical for generating healthy nerve cells that are the cornerstone of people’s stress and life-changing challenges. Therefore, the lack of leg exercise makes the body difficult to generate new nerve cells, which explains the motor neuron disease, multiple sclerosis disease, spinal muscular atrophy, and other neurological diseases when movement is limited rapid decline in neurological function the reason.

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